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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight loss in addition to a reduced-calorie diet and physical exercise.

Using two separate drugs to lose weight naturally can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err to the side of caution and allow FDA do its job and demand some investigation be done so your public is aware of the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications.

Researchers discovered that participants using this drug for any year, lost weight within a month and have kept the load off through the entire 56 weeks with the study. Contrave can be a combination from the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them more efficient and safer.

Combo-pilling will be the newest fad or also the newest to come under scrutiny and so it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that by right now there aren't long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure and heartbeat, and must not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

From a psychiatric perspective, evidence suggests that the ordinary neural mechanism for goal-directed behavior has become hijacked through the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus and the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).